to make (something) worse or more serious

annoy

(usually passive) to attack, cause trouble for, (a person, business etc) in several ways

plague; hem in

to rule (people) unjustly or cruelly; to cause (a person) to feel troubled, uncomfortable

depress, subdue

to treat (a person, group) cruelly because of beliefs or opinions

wrong, torment

to make fun of (a person) playfully or unkindly; to annoy (an animal) (e.g. by pulling its tail)

aggravate, provoke